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Index > Protein center > NDUFS3(Gene name) > Human
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  • NDUFS3 (Gene name),
  • NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (Protein name ),  NDUS3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    NDUFS3;
    Protein name:
    NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial;
    Alternative:
    NADH-ubiquinone oxidoreductase 30 kDa subunit;Complex I-30kD(CI-30kD);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Mammalian complex I is composed of 45 different subunits. Interacts with NDUFAF3.
    Function:
    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
    Subcellular Location:
    Mitochondrion inner membrane
    Protein Attributes:
    Sequence length:
    264
    Sequence:
    50:
    MAAAAVARLW | WRGILGASAL | TRGTGRPSVL | LLPVRRESAG | ADTRPTVRPR | 
    100:
    NDVAHKQLSA | FGEYVAEILP | KYVQQVQVSC | FNELEVCIHP | DGVIPVLTFL | 
    150:
    RDHTNAQFKS | LVDLTAVDVP | TRQNRFEIVY | NLLSLRFNSR | IRVKTYTDEL | 
    200:
    TPIESAVSVF | KAANWYEREI | WDMFGVFFAN | HPDLRRILTD | YGFEGHPFRK | 
    250:
    DFPLSGYVEL | RYDDEVKRVV | AEPVELAQEF | RKFDLNSPWE | AFPVYRQPPE | 
    264:
    SLKLEAGDKK | PDAK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    MIM:
    UniGene:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Cat.:
    E14622b
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Cat.:
    E14622m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    ELISA Kit for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Cat.:
    E14622h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Cat.:
    U14622b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Cat.:
    U14622h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Cat.:
    U14622m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Cat.:
    P14622Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Cat.:
    P14622Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Monoclonal Antibody for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Monoclonal Antibody for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Monoclonal Antibody for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Protein for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Protein for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
    Protein for Human NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "cDNA sequence and chromosomal localization of the remaining three human nuclear encoded iron sulphur protein (IP) subunits of complex I: the human IP fraction is completed."
      Loeffen J. , van den Heuvel L. , Smeets R. , Triepels R. , Sengers R. , Trijbels F. , Smeitink J.
      Biochem. Biophys. Res. Commun.247:751-758(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Human NDUFS3 gene coding for the 30-kDa subunit of mitochondrial Complex I: genomic organization and expression."
      Procaccio V. , Lescuyer P. , Bourges I. , Beugnot R. , Duborjal H. , Depetris D. , Mousson B. , Montfort M.F. , Smeets H. , De Coo R. , Issartel J.P.
      Mamm. Genome11:808-810(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Pituitary.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Amygdala.
      tissue: Cerebellum.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Skin.
    8. 8.
      "Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini."
      Xu G. , Shin S.B. , Jaffrey S.R.
      Proc. Natl. Acad. Sci. U.S.A.106:19310-19315(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE [LARGE SCALE ANALYSIS] OF 37-51
      tissue: Leukemic T-cell.
    9. 9.
      Lubec G. , Vishwanath V.
      Submitted (2007-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 126-136 AND 187-199;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Cajal-Retzius cell.
    10. 10.
      "The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification."
      Murray J. , Zhang B. , Taylor S.W. , Oglesbee D. , Fahy E. , Marusich M.F. , Ghosh S.S. , Capaldi R.A.
      J. Biol. Chem.278:13619-13622(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE NADH-UBIQUINONE OXIDOREDUCTASE COMPLEX;IDENTIFICATION BY MASS SPECTROMETRY
    11. 11.
      "Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease."
      Saada A. , Vogel R.O. , Hoefs S.J. , van den Brand M.A. , Wessels H.J. , Willems P.H. , Venselaar H. , Shaag A. , Barghuti F. , Reish O. , Shohat M. , Huynen M.A. , Smeitink J.A.M. , van den Heuvel L.P. , Nijtmans L.G.
      Am. J. Hum. Genet.84:718-727(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NDUFAF3
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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